Associations among neutrophil function, metabolic indicators, and reproductive health in dairy cows

The Atrium, University of Guelph Institutional Repository

Associations among neutrophil function, metabolic indicators, and reproductive health in dairy cows

Show full item record

Title: Associations among neutrophil function, metabolic indicators, and reproductive health in dairy cows
Author: Wittrock, Julie
Department: Population Medicine
Program: Population Medicine
Advisor: LeBlanc, Stephen
Abstract: This thesis is an investigation of the interactions of insulin resistance (IR), metabolic markers, neutrophil function, and reproductive health in peripartum dairy cows, including the evaluation of a hand-held glucometer for diagnosis of IR. The neutrophil functions of interest were oxidative burst and phagocytosis capacity, and reproductive diseases were endometritis and cervicitis. A total of 81 Holstein cows were enrolled 3 wk prior to expected calving date from November 2010 until October 2011, and were followed until 5 wk postpartum. Known markers of IR, neutrophil function, and disease were monitored through this period. The hand-held glucometer was identified as a useful alternative to laboratory measurements of glucose. Markers of IR influenced phagocytosis capacity and reproductive disease. High haptoglobin concentrations were associated with increased risk of reproductive disease and diminished oxidative burst function. Metabolically related inhibition of neutrophil function may be important in development of reproductive disease.
URI: http://hdl.handle.net/10214/3611
Date: 2012-05-10


Files in this item

Files Size Format View Description
Wittrock_MSc Thesis_May 2012.pdf 1.827Mb PDF View/Open Wittrock MSc Thesis

This item appears in the following Collection(s)

Show full item record

http://creativecommons.org/licenses/by-nc-nd/2.5/ca/ Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/2.5/ca/

Search the Atrium


Advanced Search

Browse

My Account